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Updated: May 13, 2025

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Chemotherapy-Induced Bone Marrow Suppression: A Bibliometrics Analysis.

Jing Yue1, Huili Shui2, Gao Li2

  • 1The First Clinical Medical School of Guizhou University of Traditional Chinese Medicine, Guizhou University of Traditional Chinese Medicine, Guiyang, People's Republic of China.

Journal of Multidisciplinary Healthcare
|April 14, 2025
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Summary

Bibliometric analysis of chemotherapy-induced bone marrow suppression reveals rising research trends. Future focus includes immunotherapy for nasopharyngeal carcinoma and novel agents like curcumin.

Keywords:
VOSviewerbibliometric analyseschemotherapy-induced bone marrow suppressioncitespacevisualization

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Area of Science:

  • Hematology
  • Oncology
  • Pharmacology

Background:

  • Chemotherapy-induced bone marrow suppression is a significant clinical challenge.
  • Understanding research trends is crucial for advancing treatment strategies.

Purpose of the Study:

  • To identify key research hotspots and evolving trends in chemotherapy-induced bone marrow suppression over the past two decades.
  • To provide a theoretical and empirical foundation for scientific and clinical advancements.

Main Methods:

  • Bibliometric visualization analysis of 6,110 documents from the Web of Science Core Database (2004-2023).
  • Utilized CiteSpace and VOSviewer software for data analysis.
  • Keyword burst detection to identify research focuses.

Main Results:

  • A significant upward trend in research volume was observed.
  • The United States and China are leading contributors.
  • Key research focuses include nasopharyngeal carcinoma, immunotherapy, nivolumab, and pembrolizumab.

Conclusions:

  • Future research should explore immune checkpoint inhibitors for nasopharyngeal carcinoma.
  • Natural compounds like curcumin and nutritional support show promise in mitigating side effects.
  • Integrative approaches combining traditional Chinese medicine with modern practices may offer synergistic benefits.