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Updated: May 13, 2025
A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
Published on: February 2, 2021
Continuous renal replacement therapy for acute kidney injury: a case report
Jianmin Wang1, Yiyao Bao1, Lijun Guan1
1Department of Surgical ICU, The Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, China.
Background:
Acute kidney injury is a severe complication of pediatric trauma with complex and diverse mechanisms and is associated with multiple organ dysfunction. For severely injured children, renal function should be closely monitored, and continuous renal replacement therapy should be promptly initiated if there is a risk of developing severe acute kidney injury. This case report describes the treatment process of a child with acute kidney injury due to trauma, highlighting the need to improve the rapid identification of traumatic acute kidney injury risk and actively implement resuscitation strategies to protect renal function in trauma patients.
Case Description:
A 3-year-old boy presented with acute kidney injury following a car accident. Multi-organ dysfunction developed, and laparotomy and liver laceration repair were performed. Continuous renal replacement therapy for 7 days, plasma exchange, antimicrobial therapy, and multi-organ support were provided. A 1-year follow-up showed no organ dysfunction.
Conclusions:
This case report describes the treatment process of a child with acute kidney injury due to trauma, highlighting the need to improve the rapid identification of traumatic acute kidney injury risk and actively implement resuscitation strategies to protect renal function in patients with trauma. Prompt continuous renal replacement therapy should be considered when necessary to prevent adverse outcomes.
