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Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

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Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
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Assessment of the Cardiovascular System III: Palpation01:27

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Palpation involves feeling the body to evaluate texture, size, consistency, and tenderness for assessing cardiovascular health. The following steps are organized in a head-to-toe order:
Jugular Venous Pressure (JVP) Measurement
Position the patient at a thirty- to forty-five-degree angle or in a semi-fowler's position. Look for the highest point of pulsation in the internal jugular vein and measure the vertical distance to the angle of Loius or sternal angle. A normal JVP is 3-4 cm above...
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Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

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Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
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Muscles of the Leg that Move the Foot and Toes01:28

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The human leg comprises an intricate system of muscles that facilitate the movement of feet and toes. Within this system, the muscles are categorized into the anterior, lateral, and posterior compartments, each with a unique set of muscles carrying out specific functions.
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Related Experiment Video

Updated: May 13, 2025

Granulocyte-dependent Autoantibody-induced Skin Blistering
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Chilblain Lupus Masquerading as Tinea Pedis.

Sarah Al Qassimi1, Fatima Abdulla2, Mohamed Elarabi1

  • 1Division of Rheumatology, Department of Internal Medicine, Cleveland Clinic Abu Dhabi, Abu Dhabi, UAE.

Oman Medical Journal
|April 14, 2025
PubMed
Summary

Chilblain lupus erythematosus is often misdiagnosed. A skin biopsy is crucial for accurate diagnosis, preventing incorrect treatments for this lupus subtype.

Keywords:
BiopsyChilblain lupus 1DermatologyLupus Erythematosus, DiscoidRheumatology

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Area of Science:

  • Dermatology
  • Rheumatology
  • Pathology

Background:

  • Chilblain lupus erythematosus (CLE) presents with varied symptoms, leading to frequent misdiagnosis.
  • Early and accurate diagnosis of CLE is essential for effective patient management.

Observation:

  • A case report details a young Jordanian male with recurrent misdiagnoses.
  • The patient's condition was ultimately diagnosed via skin biopsy.

Findings:

  • Skin biopsy confirmed the diagnosis of chilblain lupus erythematosus.
  • Histopathological examination is key to differentiating CLE from other conditions.

Implications:

  • Emphasizes the diagnostic utility of skin biopsy in challenging dermatological cases.
  • Highlights the need for increased awareness of CLE among clinicians to avoid delayed or incorrect treatment.
  • Accurate diagnosis prevents unnecessary and potentially harmful therapeutic interventions.