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A Rare Case of Pituicytoma During Pregnancy
Junchen Wu1, Hao Tang1, Bo Zhang1
1Department of Neurosurgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Jiao Tong University, Shanghai 200001, China.
Abstract:
Pituicytomas are rare benign sellar tumors that originate in the neurohypophysis. We report the first case of a pituicytoma during pregnancy, causing headaches and bilateral temporal visual field defects. A 32-year-old woman at 16 weeks of gestation was admitted to our hospital for headaches and progressively worsening visual impairment. Cranial magnetic resonance imaging (MRI) revealed a sellar lesion that was resected via a neuroendoscopic endonasal-transsphenoid approach. Pathology revealed a pituicytoma with positive progesterone receptor expression. After cerebrospinal fluid (CSF) leakage repair and anti-infective therapy, the patient recovered well and finally gave birth to a healthy child. This is the first case of pituicytoma during pregnancy reported. Pregnancy may have a contributing effect on the progression of progesterone receptor-positive pituicytomas. Surgical intervention, when performed with appropriate perioperative management, can effectively alleviate mass effects caused by pituicytomas in pregnant women while maintaining the safety of the fetus.
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