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Updated: May 13, 2025

Establishment of an Experimental Mouse Model of Endometrioma to Study its Related Infertility
Published on: April 5, 2024
Advances in endometriosis research: animal models for the study of reproductive disorders
Mingjuan Zhou1, Xingchen Zhou1, Xipeng Wang1
1Department of Obstetrics and Gynecology, XinHua Hospital, Shanghai Jiaotong University School of Medicine, 1665 Kongjiang Rd, Yangpu District, Shanghai, 200092, China.
Abstract:
Endometriosis (EMS) is a significant contributor to female infertility, with its underlying mechanisms remaining inadequately understood. Animal models serve as essential tools for investigating disease progression and evaluating treatment options. This article reviews the advancements in research involving animal models, including nonhuman primates and rodents, in the development of EMS-related infertility models. This study provides a comprehensive overview of the latest advancements in understanding the mechanisms of infertility related to EMS in animal models. It serves as a valuable resource for researchers seeking guidance in choosing suitable animal models for investigations on the pathogenesis and pharmacological treatment of this condition.

