Related Experiment Video
Updated: May 13, 2025
Micro-dissection of Enamel Organ from Mandibular Incisor of Rats Exposed to Environmental Toxicants
Published on: March 29, 2018
Developmental defects of enamel and dental anomalies in children with skin diseases
Alev Eda Okutan1, Ayşe Deniz Yücelten2, Ali Menteş3
1Private Practice, Istanbul, Turkey. alevedaokutan@gmail.com.
Objectives:
The ectodermal origin of enamel and skin suggests a potential link between dermatological conditions and dental anomalies. This study aimed to evaluate the prevalence of developmental defects of enamel (DDE) and other dental anomalies in pediatric patients with skin diseases.
Materials And Methods:
This cross-sectional study included 71 pediatric patients (aged 4-14) diagnosed with chronic skin diseases or genodermatoses, along with 41 age- and sex-matched controls. Enamel defects were assessed using both the Modified DDE Index and the Molar-Incisor Hypomineralization (MIH) Index, while panoramic radiographs were analyzed for hypodontia, taurodontism, short root anomaly, and primary failure of eruption.
Results:
DDE-not-related MIH was significantly higher in the study group (p = 0.01). Additionally, other dental anomalies were significantly more prevalent in the study group (p = 0.03), particularly among patients with genodermatoses (p < 0.001). Ectodermal dysplasia and epidermolysis bullosa exhibited the highest prevalence of dental anomalies.
Conclusion:
Our findings suggest a possible association between skin diseases, particularly genodermatoses, and an increased prevalence of dental anomalies. These results highlight the importance of early dental screening and multidisciplinary care for children with dermatological conditions.
Clinical Relevance:
Understanding the dental implications of skin diseases can aid clinicians in early diagnosis and preventive strategies, improving oral health outcomes for affected children.
Related Concept Videos
01:23Skin Diseases and Disorders
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
01:15Teeth
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
01:14Changes in Skin Color: Clinical Perspectives
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
01:21Tooth Anatomy
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or...
01:26Minerals
Major...
01:29Bone Disorders
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...