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Updated: May 13, 2025

Monitoring Tumor Metastases and Osteolytic Lesions with Bioluminescence and Micro CT Imaging
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Unveiling Another Dimension: Advanced Visualization of Cancer Invasion and Metastasis via Micro-CT Imaging

Sergey Tkachev1, Vladimir Brosalov2, Oleg Kit3

  • 1Institute for Regenerative Medicine, Sechenov University, 119992 Moscow, Russia.

Cancers
|April 14, 2025
PubMed

Abstract:

Invasion and metastasis are well-known hallmarks of cancer, with metastatic disease accounting for 60% to 90% of cancer-related deaths [...].

Keywords:
cancer invasioncell migrationesophageal squamous cell carcinomainvasion patternsmetastasismicro-CTpatient-derived xenograft modelstumor biologytumor buddingxenografts

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Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
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The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
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Keywords:
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