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When two debilitating diseases collide: frailty and diabetic foot
Hikmet Erhan Güven1, Mehtap Günel2, Cansu Cambaz2
1MD, Professor of Surgery, University of Health Sciences, Ankara Etlik City Hospital, Department of General Surgery, Diabetic Foot and Chronic Wounds, Ankara, Turkey.
Journal of Wound Care
|April 14, 2025
Summary
Diabetic foot (DF) can cause frailty in patients under 65. Frailty in DF patients is linked to advanced disease stages and higher rates of minor amputations.
Area of Science:
- Medical Research
- Clinical Medicine
- Diabetology
Background:
- Diabetic foot (DF) is a significant complication of diabetes.
- Frailty is typically associated with older adults, but its presence in younger populations with DF is less understood.
Purpose of the Study:
- To assess the prevalence of frailty among patients under 65 presenting with diabetic foot.
- To identify factors contributing to frailty in this demographic.
Main Methods:
- A prospective study included 97 patients under 65 with DF from January to September 2023.
- The Clinical Frailty Scale (CFS) assessed frailty at initial presentation.
- Patients were categorized as non-frail (CFS 1-4) or frail (CFS ≥5).
Main Results:
- 37.1% of patients (36 out of 97) were classified as frail.
- Frail patients demonstrated significantly higher rates of advanced Wagner stages 3 and 4 DF (p<0.001).
- Minor amputations were required for 52.7% of frail patients compared to 24.6% of non-frail patients (p=0.005).
Conclusions:
- Diabetic foot can induce frailty even in non-geriatric populations.
- Frailty in patients under 65 with DF correlates with disease severity and increased likelihood of minor amputations.
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