Enhanced Recovery After Surgery Protocol in Patients With Adult Spinal Deformity: A Systematic Review and...

Study DesignSystematic review and meta-analysis.ObjectivesPerioperative interventions in Enhanced recovery after surgery (ERAS) protocols for managing adult spinal deformity (ASD) patients vary widely across institutions without widespread standardization. This study aims to evaluate the various interventions performed in ERAS protocols and the impact of these protocols on postoperative outcomes following ASD surgery.MethodsA comprehensive systematic review was conducted following PRISMA guidelines. Studies that addressed the implementation of ERAS protocol for thoraco-lumbar corrective surgery were included. We conducted a meta-analysis on postoperative outcomes, where possible, calculating the pooled standardized mean difference between conventional care (pre-ERAS) and ERAS pathways (post-ERAS).ResultsOut of 63 articles, 8 were included in the systematic review. Common interventions in the ERAS protocols included: (1) preoperative anesthesia-related risk assessment and multidisciplinary assessment, (2) intraoperative tranexamic acid (TXA) administration and continuous monitoring of lab data, and (3) postoperative early mobilization and early nutritional support. Multimodal analgesia plans were commonly observed in many of the ERAS protocols. Although meta-analysis demonstrated no significant difference in length of stay (LOS) between the groups, the post-ERAS group generally tended to exhibit lower rates of readmission and medical complications, and reductions in total opioid consumption.ConclusionsThe goals of ERAS protocols for ASD surgery often address preoperative optimization, intraoperative stress minimization, and postoperative recovery facilitation. While the implementation of the ERAS protocol has shown improvements in postoperative outcomes, further studies are required to standardize the ERAS protocol for ASD surgery and enhance the impact on multiple postoperative outcomes.