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A description of human placental syncytiotrophoblast membrane glycosphingolipids
Placenta
|May 1, 1985
Abstract:
The glycosphingolipid (GSL) structure of isolated human term placental syncytiotrophoblast microvillous plasma membrane (StMPM) has been investigated by Folch solvent extraction and thin-layer chromatography. StMPM preparations were shown to contain unique hydrophilic GSL species, including two highly glycosylated (greater than 15 saccharide residues/molecule) components. This fraction consistently included four major gangliosides (sialylated GSL), as well as two highly-sialylated (greater than or equal to 4 sialic acid residues/molecule) minor gangliosides.