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Arteriovenous Thrombosis among Severe Acute Respiratory Syndrome Coronavirus 2 Infected Patients: An Observational
Abdullah Saleh AlAmri1,2, Mohammad S AlShahrani2,3, Tareq Mohammed Hejazi4
1Department of Neurology, King Fahd Hospital of the University, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
Context:
The global spread of severe acute respiratory syndrome coronavirus 2 since its emergence in 2019 has led to widespread challenges in healthcare, prompting the World Health Organization to declare it a pandemic.
Aim:
The aims of this study were to explore the prevalence of arterio-venous thrombosis (AVT) in COVID-19 patients, along with baseline characteristics and predictors of AVT.
Settings And Design:
This retrospective cohort study review of charts from adult patients presenting between March 1, 2020, and October 30, 2021, at King Fahd Hospital of the University.
Subjects And Methods:
Patients with both AVT and COVID-19 were included and categorized into groups: brain stroke, myocardial infarction (MI), pulmonary embolism (PE), and deep venous thrombosis (DVT). Demographic and clinical data were collected from electronic medical records, and patients were followed up 1 year after discharge.
Statistical Analysis Used:
SPSS was used.
Results:
Five hundred nine adult patients were admitted with COVID-19, and 195 were diagnosed with AVT. Brain stroke, MI, PE, and DVT were observed in 48.7%, 25.6%, 10.8%, and 14.9% of cases, respectively. Risk factors such as hypertension, diabetes, dyslipidemia, and smoking were more prevalent among stroke patients. Follow-up revealed varying mortality rates and recurrent AVT cases among different AVT syndromes.
Conclusions:
The study highlights a higher incidence of AVT, particularly brain stroke, in COVID-19-positive patients, with overlapping AVT syndromes observed. The findings emphasize the intricate relationship between COVID-19 and AVT, necessitating further research and targeted interventions to address this critical aspect of the disease.
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