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Related Concept Videos

Epistaxis01:30

Epistaxis

112
Epistaxis, or nosebleeds, occurs when small, swollen blood vessels in the nasal mucous membrane rupture. Typically, the anterior septum is the primary site of occurrence.
Etiology
Possible causes of this condition include high blood pressure, trauma, low humidity, upper respiratory tract infections, allergies, foreign bodies, nasal inhalation of corticosteroids or illicit drugs, excessive use of decongestant nasal sprays, facial or nasal surgery, anatomic malformation, tumors, or systemic...
112

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Related Experiment Video

Updated: May 13, 2025

Establishing a Severe Corneal Inflammation Model in Rats Based on Corneal Epithelium Curettage Combined with Corneal Sutures
04:48

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Published on: November 22, 2024

185

Severe Epistaxis Due to Risankizumab: A Case Report.

Judith P Vinod1, Nicholas Gallo1, Julio Gonzalez2

  • 1Internal Medicine, Nova Southeastern University Dr. Kiran C. Patel College of Osteopathic Medicine, Fort Lauderdale, USA.

Cureus
|April 15, 2025
PubMed
Summary

Risankizumab effectively treats plaque psoriasis but can cause side effects. This report details a case of severe epistaxis (nosebleeds) in a patient undergoing risankizumab treatment.

Area of Science:

  • Immunodermatology
  • Pharmacology
  • Clinical Medicine

Background:

  • Risankizumab is an interleukin-23 inhibitor approved for plaque psoriasis treatment.
Keywords:
il-23 inhibitorsimmunotherapy-related adverse eventsmanagement of severe epistaxisrisankizumabs: epistaxissevere epistaxis

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  • It is a humanized monoclonal antibody known for efficacy and safety in clinical trials.
  • Nasopharyngitis is the most common adverse effect, reported in over 20% of users.