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Updated: May 13, 2025

Assessment of the Metabolic Profile of Primary Leukemia Cells
Published on: November 21, 2018
Biopsychosocial needs of leukemic children - A systematic review
Kannan Kasinathan1, Rajamanickam Rajkumar2, Shankar Shanmugam Rajendran3
1Research Scholar, Meenakshi Academy of Higher Education & Research(DU), Chennai & Department of Child Health Nursing, College of Nursing, Madras Medical College, Chennai , India.
Insights
Pediatric leukemia survival is high, but early detection and post-treatment psychosocial support need improvement. Comprehensive care addressing medical, emotional, and social needs is vital for children with leukemia.
Area of Science:
- Pediatric Oncology
- Childhood Cancer Research
- Hematology
Background:
- Leukemia, including Acute Lymphoblastic Leukaemia (ALL) and Acute Myeloblastic Leukaemia (AML), is a significant cause of mortality in children.
- While survival rates have improved to 80-90% due to advanced treatments, early detection remains a challenge, often relying on non-standardized methods.
- Adherence to early recognition guidelines is crucial for timely diagnosis and intervention.
Purpose of the Study:
- To systematically review the biopsychosocial needs of children diagnosed with leukemia.
- To identify gaps in post-treatment care and evaluate the impact on mental health, emotional well-being, and quality of life.
- To emphasize the need for standardized assessment methods and tailored interventions.
Main Methods:
- A systematic review was conducted adhering to the PRISMA guidelines.
- The review focused on literature concerning the biopsychosocial aspects of pediatric leukemia.
- Data extraction and synthesis were performed to identify key findings regarding patient needs.
Main Results:
- Significant gaps were identified in post-treatment care for pediatric leukemia patients.
- Parent education emerged as a critical factor in managing the challenges faced by children.
- The review highlighted the necessity of integrated approaches to manage psychosocial and emotional difficulties.
Conclusions:
- Tailored interventions addressing medical, emotional, and social needs are essential for enhancing symptom control and quality of life in children with leukemia.
- Improved adherence to early recognition guidelines and standardized assessment methods are required.
- Further research is needed to develop and validate comprehensive care strategies for pediatric leukemia survivors.
Abstract:
Leukaemia, particularly Acute Lymphoblastic Leukaemia (ALL) and Acute Myeloblastic Leukaemia (AML), is the second leading cause of death among children aged 0-14, with survival rates of 80-90% achieved through improved treatment. Despite these advancements, challenges persist in early detection, as most cases are identified through non-standardized methods, highlighting the need for better adherence to guidelines for early recognition. A systematic review following PRISMA guidelines explored the biopsychosocial needs of children with leukaemia, focusing on mental health, emotional well-being and quality of life. The review identified significant gaps in post-treatment care, emphasized the importance of parent education and underscored the necessity for comprehensive approaches to address psychosocial and emotional challenges. Tailored interventions that address medical, emotional and social needs are crucial to improving symptom control and quality of life. In contrast, further research is needed to standardise assessment methods for pediatric leukaemia patients.
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