Related Experiment Video

Updated: May 13, 2025

Delivery of the Cas9/sgRNA Ribonucleoprotein Complex in Immortalized and Primary Cells via Virus-like Particles "Nanoblades"
09:23

Delivery of the Cas9/sgRNA Ribonucleoprotein Complex in Immortalized and Primary Cells via Virus-like Particles "Nanoblades"

Published on: March 31, 2021

4.8K

Glutathione-responsive Nanoparticles for Optimized Cas9/sgRNA Gene Editing Delivery

Md Sadique Hussain1, Ajay Singh Bisht2, Haider Ali3,4

  • 1Uttaranchal Institute of Pharmaceutical Sciences, Uttaranchal University, Dehradun, Uttarakhand, 248007, India.

Current Drug Targets
|April 15, 2025
PubMed
Summary

No abstract available in PubMed .

Keywords:
CRISPR-Cas9Gene editingbiocompatibilitycontrolled release systemsgene therapy.glutathione-responsive systemslipid nanoparticlesnanocarrierstargeted drug deliverytumor microenvironment

More Related Videos

Enhanced Genome Editing with Cas9 Ribonucleoprotein in Diverse Cells and Organisms
09:51

Enhanced Genome Editing with Cas9 Ribonucleoprotein in Diverse Cells and Organisms

Published on: May 25, 2018

33.6K
Using Lipid Nanoparticles for the Delivery of Chemically Modified mRNA into Mammalian Cells
10:02

Using Lipid Nanoparticles for the Delivery of Chemically Modified mRNA into Mammalian Cells

Published on: June 10, 2022

2.1K

Related Experiment Videos

Last Updated: May 13, 2025

Delivery of the Cas9/sgRNA Ribonucleoprotein Complex in Immortalized and Primary Cells via Virus-like Particles "Nanoblades"
09:23

Delivery of the Cas9/sgRNA Ribonucleoprotein Complex in Immortalized and Primary Cells via Virus-like Particles "Nanoblades"

Published on: March 31, 2021

4.8K
Enhanced Genome Editing with Cas9 Ribonucleoprotein in Diverse Cells and Organisms
09:51

Enhanced Genome Editing with Cas9 Ribonucleoprotein in Diverse Cells and Organisms

Published on: May 25, 2018

33.6K
Using Lipid Nanoparticles for the Delivery of Chemically Modified mRNA into Mammalian Cells
10:02

Using Lipid Nanoparticles for the Delivery of Chemically Modified mRNA into Mammalian Cells

Published on: June 10, 2022

2.1K

Related Concept Videos

CRISPR01:59

CRISPR

48.6K
Genome editing technologies allow scientists to modify an organism’s DNA via the addition, removal, or rearrangement of genetic material at specific genomic locations. These types of techniques could potentially be used to cure genetic disorders such as hemophilia and sickle cell anemia. One popular and widely used DNA-editing research tool that could lead to safe and effective cures for genetic disorders is the CRISPR-Cas9 system. CRISPR-Cas9 stands for Clustered Regularly Interspaced...
48.6K

Articles linked to this work by shared authors, journal, and citation graph.

Correction: Wali et al. Epigenetic Alterations in Hepatocellular Carcinoma: Mechanisms, Biomarkers, and Therapeutic Implications. Pharmaceuticals 2025, 18, 1281.

Pharmaceuticals (Basel, Switzerland)·2026

In silico Exploration of Aegle Marmelos-Derived Compounds as Potential Inhibitors of NS5 RdRp in Japanese Encephalitis Virus.

Combinatorial chemistry & high throughput screening·2026

Unlocking the Role of Exosomal ncRNAs in Colorectal Cancer: Molecular Insights and Clinical Promise.

Current pharmaceutical design·2026

The molecular landscape of kidney stone disease: pathophysiology to personalized intervention.

Drug metabolism and personalized therapy·2026

Phytochemical-Based Strategies for Lung Cancer: Clinical Insights Into Pleiotropic Molecular Signaling and Therapeutic Roles.

Phytotherapy research : PTR·2026

Repurposing DPP-4 inhibitors as anticancer agents in KRAS-mutated pancreatic ductal adenocarcinoma.

BMC pharmacology & toxicology·2025

Quercetin as an Adjuvant in Cancer Therapy: Biological Mechanisms, Oral Delivery Systems, and Clinical Perspectives.

Current drug targets·2026

Bioinformatic Tools to Explore the Mechanisms and the Multitarget Recognition of Huperzine A in Alzheimer's and Parkinson's Diseases.

Current drug targets·2026

Exploring the Bioactive Components and Therapeutic Targets of Sanzi Decoction in Antihypertensive Treatment.

Current drug targets·2026

Hawthorn (Crataegus Species): Phytochemical Insights and Cardiotonic Mechanisms in Cardiovascular Health- A Comprehensive Review.

Current drug targets·2026

Blockade of the GDF15/GFRAL Axis: Translational Advances in Cachexia, Immune Suppression, and Beyond.

Current drug targets·2026

Barbatolic Acid Prevents Tau and Amylin Interaction and Stimulates the Growth of Acetylated Microtubules in Cell Culture.

Current drug targets·2026

Nanoscale Confinement Enhances Ultrafast Demagnetization.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026

Nanosomes in Precision Nanomedicine (Second Edition).

Nanomaterials (Basel, Switzerland)·2026

Antimicrobial Effect of Silver Nanoparticles Capped with Killer Yeast-Derived Protein Fractions.

Nanomaterials (Basel, Switzerland)·2026

Dynamic Liquid-like Membrane Gates Mass Transport in Inorganic Nanocells.

Nano letters·2026

Reticular Chemistry for Next-Generation Micro-/Nanoswimmers: Modular Construction and Dynamic Functionality.

Nano letters·2026

Assembly and Disassembly of Nanoparticles for Antitumor Applications: Mechanisms, Strategies, and Functions.

Advanced materials (Deerfield Beach, Fla.)·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies
Jove
Visualize
Contact Us