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Configurable Vibrational Coupling in Laser-Induced Microsecond Oscillations of Multi-Microbubble System.
Xuanwei Zhang1, Ryu Matsuo1, Yusuke Yahano1
1Department of Micro Engineering, Kyoto University, Nishikyo-ku, Kyoto, 615-8540, Japan.
Small (Weinheim an Der Bergstrasse, Germany)
|April 15, 2025
Summary
Precise control over laser-induced microbubble spacing enables complex flow patterns. This breakthrough in microfluidics allows for regulated spatial and temporal fluid dynamics previously unachievable.
Area of Science:
- Fluid dynamics
- Microfluidics
- Acoustics
Background:
- Microbubbles oscillate and generate localized flows.
- Multiple microbubbles can create complex, regulated flow profiles.
- Controlling microbubble proximity and interactions is challenging.
Purpose of the Study:
- To demonstrate precise control over the separation of two laser-induced microbubbles.
- To investigate the coupled dynamics and flow profiles of nearby microbubbles.
- To explore new possibilities for generating complex spatiotemporal flows in microfluidics.
Main Methods:
- Generating two laser-induced microbubbles with precise, configurable separations (14–92 µm).
- Utilizing photothermal heating for microbubble generation and sub-MHz oscillation frequencies.
- Capturing microbubble dynamics in real-time with a high-speed camera.
- Employing an extended Rayleigh-Plesset equation to model pressure interactions.
Main Results:
- Observed hybridized in-phase and anti-phase vibrations for closely spaced bubbles (< 50 µm).
- Quantitatively reproduced distance-dependent coupled oscillation frequencies (0.5–0.8 MHz).
- Demonstrated that microbubble proximity significantly alters oscillation profiles compared to isolated bubbles.
Conclusions:
- Precise control over microbubble separation enables tunable interactions.
- Coupled microbubble dynamics can generate complex, regulated spatiotemporal flows.
- This research opens avenues for advanced microfluidic applications using microbubble arrays.

