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Updated: May 13, 2025

Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation
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Founder Variants in the Mexican Population: A Systematic Review

Sylvia Harari-Arakindji1, Teresa Metta-Harari1, Isabel Espino-Gutiérrez2

  • 1Facultad de Ciencias de la Salud, Universidad Anáhuac México Norte, Mexico City, Mexico.

Archives of Medical Research
|April 15, 2025
PubMed
Summary

This study identifies 21 founder variants (FVs) in 19 genes linked to diseases in the Mexican population. Some frequent variants may have European origins, offering insights into genetic history and health.

Keywords:
CancerFounder mutationFounder variantsGenetic syndromesLatin AmericaMexican population

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