Endoscopic direct diverticulitis therapy for acute uncomplicated diverticulitis
Jian-Zhen Ren1, Jun Cai1, Bo Li1
1Department of Gastroenterology, South China Hospital, Medical School, Shenzhen University, Shenzhen, China.
Endoscopy
|April 15, 2025
Summary
Endoscopic direct diverticulitis therapy (EDDT) is a promising new treatment for acute uncomplicated diverticulitis. This technique demonstrated high success rates and immediate symptom relief in a small patient group.
Area of Science:
- Gastroenterology
- Endoscopic procedures
- Diverticular disease management
Background:
- Acute uncomplicated diverticulitis prevalence is rising globally.
- Current patient care is undergoing significant transformation.
- Novel therapeutic approaches are needed for effective management.
Purpose of the Study:
- To assess the diagnostic and therapeutic efficacy of endoscopic direct diverticulitis therapy (EDDT).
- To evaluate cholangioscope-assisted colonoscopy as a tool for EDDT in acute uncomplicated diverticulitis.
Main Methods:
- Retrospective analysis of 12 patients with CT-confirmed acute uncomplicated diverticulitis (Hinchey Ia/Ib).
- Patients underwent EDDT using cholangioscope-assisted colonoscopy between July 2023 and December 2024.
- Data collected included technical success, procedure time, endoscopic findings, symptom resolution, and recurrence.
Main Results:
- 100% technical success rate for EDDT in all 12 patients.
- Common endoscopic findings included fecaliths with pus and purulent collections.
- Immediate resolution of abdominal pain and normalization of inflammatory markers were observed.
Conclusions:
- EDDT with cholangioscope-assisted colonoscopy is a feasible and effective treatment for acute uncomplicated diverticulitis.
- The technique offers direct visualization for diagnosis and therapy.
- Preliminary findings are promising, but larger studies are required to confirm long-term outcomes.
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