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Related Experiment Video

Updated: Jul 2, 2026

Quantitative Assessment of Cortical Auditory-tactile Processing in Children with Disabilities
09:38

Quantitative Assessment of Cortical Auditory-tactile Processing in Children with Disabilities

Published on: January 29, 2014

Does general anaesthesia affect the child's auditory middle latency response (MLR)?

S Prosser, E Arslan

    Scandinavian Audiology
    |January 1, 1985
    PubMed
    Summary

    General anesthesia significantly impacts auditory neural activity in children. Auditory Middle Latency Responses (MLR) showed abnormalities, unlike Auditory Brainstem Responses (ABR), suggesting CNS drug effects.

    Area of Science:

    • Neuroscience
    • Audiology
    • Pediatric Anesthesiology

    Background:

    • Auditory evoked potentials are crucial for assessing auditory pathway function.
    • General anesthesia can influence central nervous system (CNS) activity, potentially affecting electrophysiological measures.
    • Understanding these effects is vital for accurate hearing assessments in pediatric patients.

    Purpose of the Study:

    • To investigate the impact of general anesthesia on auditory evoked potentials in children.
    • To compare the effects on Auditory Middle Latency Response (MLR) versus Auditory Brainstem Response (ABR).

    Main Methods:

    • Simultaneous recording of Auditory MLR and ABR in 9 children.
    • Children underwent testing under general anesthesia.
    • Normal hearing thresholds were confirmed via electrocochleography prior to testing.

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    Behavioral Assessment of Hearing in 2 to 4 Year-old Children: A Two-interval, Observer-based Procedure Using Conditioned Play-based Responses

    Published on: January 23, 2017

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    Last Updated: Jul 2, 2026

    Quantitative Assessment of Cortical Auditory-tactile Processing in Children with Disabilities
    09:38

    Quantitative Assessment of Cortical Auditory-tactile Processing in Children with Disabilities

    Published on: January 29, 2014

    Infant Auditory Processing and Event-related Brain Oscillations
    06:34

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    Published on: July 1, 2015

    Behavioral Assessment of Hearing in 2 to 4 Year-old Children: A Two-interval, Observer-based Procedure Using Conditioned Play-based Responses
    14:05

    Behavioral Assessment of Hearing in 2 to 4 Year-old Children: A Two-interval, Observer-based Procedure Using Conditioned Play-based Responses

    Published on: January 23, 2017

    Main Results:

    • Auditory Brainstem Response (ABR) components were clearly recognizable with normal latencies.
    • Auditory Middle Latency Response (MLR) exhibited significant abnormalities, including component instability and abnormal peak latencies.
    • These MLR variations suggest a direct consequence of general anesthesia.

    Conclusions:

    • General anesthesia appears to induce gross abnormalities in Auditory MLR in children.
    • The findings suggest that CNS drugs used in anesthesia affect neural activity reflected in MLR.
    • ABR remains a more stable measure under these conditions, while MLR requires careful interpretation in anesthetized children.