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Updated: May 13, 2025

Preparation of Synaptic Plasma Membrane and Postsynaptic Density Proteins Using a Discontinuous Sucrose Gradient
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Ykt6 SNARE protein drives GluA1 insertion at synaptic spines during LTP

Momoko Takahashi, Gabriela Caraveo

    Biorxiv : the Preprint Server for Biology
    |April 16, 2025
    PubMed
    Summary

    Ykt6, a protein regulating endoplasmic reticulum (ER) trafficking, is crucial for synaptic plasticity and memory formation in the hippocampus. Its dysfunction is linked to neurodegenerative diseases like Lewy Body Dementias (LBDs).

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