Related Experiment Video
Updated: May 13, 2025

Urethral Stricture Induction Followed by Buccal Mucosa Graft Urethroplasty in a Rat Model
Published on: April 28, 2023
Unusual presentation of cowper gland adenocarcinoma Mimicking post-traumatic urethral stricture
Babak K Azad1, Hung L Do2, Joel Gelman3
1Tulane University School of Medicine, United States.
Abstract:
Urethral strictures are commonly attributed to trauma, inflammation, or iatrogenic causes, but malignancies are a rare etiology. We report a case of a 57-year-old male with a history of trauma presenting with a bulbomembranous urethral stricture, initially suspected as post-traumatic. Intraoperative frozen section analysis unexpectedly revealed Cowper gland adenocarcinoma, leading to definitive surgical management with radical cystoprostatectomy and urethrectomy. This case underscores the importance of considering malignancy in atypical stricture presentations to ensure accurate diagnosis and appropriate treatment.

