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Persistent Abdominal Pain and Diarrhea After Appendectomy-Crohn's Disease Versus Intestinal Tuberculosis
Jonas Wizenty1,2, Martin Maibier1, Michael Sigal1,3
1Department of Hepatology and Gastroenterology Charité-Universitätsmedizin Berlin Berlin Germany.
Summary
Intestinal tuberculosis is a rare mimic of Crohn's disease in Western Europe. Early diagnosis requires considering tuberculosis culture in patients with positive Interferon-Gamma Release Assays and suspected Crohn's disease.
Area of Science:
- Gastroenterology
- Infectious Diseases
- Differential Diagnosis
Background:
- Intestinal tuberculosis (ITB) is an uncommon cause of abdominal symptoms in Western Europe.
- ITB can present similarly to Crohn's disease, posing a diagnostic challenge.
Purpose of the Study:
- To report a case of ITB misdiagnosed as Crohn's disease.
- To emphasize the importance of microbiological confirmation for ITB.
Main Methods:
- Case presentation of a 59-year-old female with persistent abdominal pain and diarrhea.
- Initial suspicion of Crohn's disease.
- Diagnostic workup including Interferon-Gamma Release Assay (IGRA).
Main Results:
- The patient presented with symptoms mimicking Crohn's disease.
- Interferon-Gamma Release Assay (IGRA) was positive.
- The final diagnosis was intestinal tuberculosis.
Conclusions:
- Intestinal tuberculosis should be considered in the differential diagnosis of Crohn's disease, especially in endemic or at-risk populations.
- Tuberculosis culture is crucial for confirming ITB in patients with positive IGRA and symptoms suggestive of Crohn's disease.
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