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A Whole Body Dosimetry Protocol for Peptide-Receptor Radionuclide Therapy PRRT: 2D Planar Image and Hybrid 2D+3D SPECT/CT Image Methods
Published on: April 24, 2020
Misadministration of 177 Lu-DOTATATE Instead of 177 Lu-PSMA in a Patient With Prostate Cancer: Clinical Implications
Mohammad Hadi Samadi1, Pegah Sahafi1, Susan Khezri2
1Nuclear Medicine Research Center, Mashhad University of Medical Science.
Abstract:
We present a 62-year-old man with a history of very high-risk prostate cancer (Gleason score: 4+3 in 12 of 12 cores) and widespread skeletal metastases was referred for 177 Lu-PSMA therapy in the setting of metastatic castration-resistant prostate cancer (mCRPC). In the second session of the treatment, misadministration of 177 Lu-DOTATATE instead of 177 Lu-PSMA occurred. Post-treatment Lutetium whole body scan and SPECT/CT showed faint uptake in the prostate gland and seminal vesicles with skeletal metastases. Our case emphasizes the importance of encouraging colleagues to report medical errors and concerns about safety protocols for minimizing errors in the nuclear medicine department.
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