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Published on: April 12, 2021
Feasibility, Acceptability, and Effectiveness of a Smartphone App to Increase Pretransplant Vaccine Rates: Usability
Amy G Feldman1,2,3, Brenda L Beaty1,3, Susan L Moore1,3,4
1Section of Pediatric Gastroenterology, Hepatology, and Nutrition, University of Colorado, 13123 E 16th Ave, Aurora, CO, 80045, United States, 1 720-777-5354.
Insights
The Immunize PediatricTransplant app significantly improved vaccine rates in children awaiting transplants, with 96% up-to-date at transplant. Parents and providers found the mobile health tool feasible and acceptable for managing pretransplant vaccinations.
Area of Science:
- Pediatric transplantation
- Infectious disease prevention
- Mobile health technology
Background:
- Vaccine-preventable infections pose significant risks to pediatric transplant recipients, leading to morbidity, mortality, and high healthcare costs.
- Less than 20% of children awaiting transplant are up-to-date on age-appropriate vaccines, increasing their vulnerability.
- Mobile health applications offer a promising strategy to enhance pretransplant vaccination rates.
Purpose of the Study:
- To conduct phase 2 beta testing of the Immunize PediatricTransplant smartphone app.
- To evaluate the app's effectiveness in achieving up-to-date vaccine status by transplant.
- To assess the feasibility and acceptability of the app for parents and transplant providers.
Main Methods:
- Recruited 25 parent-provider dyads for children awaiting liver, kidney, or heart transplants.
- Utilized questionnaires for baseline and post-use data collection on app feasibility and acceptability.
- Entered vaccine records into the app, which users accessed for viewing records, education, communication, and reminders.
Main Results:
- 96% of children achieved up-to-date vaccine status by the time of transplant.
- 97% of users felt more knowledgeable about pretransplant vaccines, and 86% reported improved communication.
- High recommendation rates for the app: 91% of parents and 79% of providers suggested future use.
Conclusions:
- The Immunize PediatricTransplant app demonstrated high effectiveness and user acceptance in improving pretransplant vaccination rates.
- Future iterations should explore electronic health record integration for seamless data transfer.
- Widespread adoption of this app could reduce post-transplant infections and improve patient outcomes.
Background:
Vaccine-preventable infections result in significant morbidity, mortality, and costs in pediatric transplant recipients. Despite intensive medical care in the pretransplant period, less than 20% of children are up to date for age-appropriate vaccines at the time of transplant. Mobile health apps have the potential to improve pretransplant vaccine rates.
Objective:
This paper aimed to perform phase 2 beta testing of the smartphone app, Immunize PediatricTransplant, to determine (1) if it was effective in achieving up-to-date vaccine status by the time of transplant in a cohort of children awaiting transplants and (2) if the app was feasible and acceptable to parent and transplant provider users.
Methods:
We recruited 25 dyads of parents and providers of a child awaiting a liver, kidney, or heart transplant at Children's Hospital Colorado, Ann and Robert H. Lurie Children's Hospital, and the Children's Hospital of Philadelphia. Parents and providers filled out an entry questionnaire before app use to gather baseline information. A research team member entered the child's vaccine records into the app. The parent and provider downloaded and used the app until the transplant to view vaccine records, read vaccine education, communicate with team members, and receive overdue vaccine reminders. After the transplant (or on April 1, 2024, the conclusion of the study), the parent and provider filled out an exit questionnaire to explore feasibility and acceptability of the app. The child's vaccine records were reviewed to determine if the child was up to date on vaccines at the time of transplant.
Results:
Twenty-five parent and provider dyads were enrolled; 56% (14/25) had a child awaiting a liver transplant, 28% (7/25) had a child awaiting a kidney transplant, and 16% (4/25) had a child awaiting a heart transplant. At the conclusion of the study, 96% (24/25) of the children were up to date on vaccines. Of the 36 parents and providers who filled out an exit questionnaire, 97% (n=35) agreed or strongly agreed that they felt knowledgeable about pretransplant vaccine use and 86% (n=31) agreed or strongly agreed that communication around vaccines was good after using the app. Further, 91% (20/22) of parents and 79% (11/14) of providers recommended the app to future parents and providers of transplant candidates. Parents and providers suggested that in the future the app should connect directly to the electronic medical record or state vaccine registries to obtain vaccine data.
Conclusions:
The overwhelming majority of children whose parents and providers used the Immunize PediatricTransplant app were up to date on vaccines at the time of transplant. The majority of app users felt the app was feasible and acceptable. In future iterations of the app and subsequent clinical trials, we will explore whether application programming interfaces might be used to extract vaccine data from the electronic medical record. If implemented broadly, this app has the potential to improve pretransplant vaccine rates, resulting in fewer posttransplant infections and improved posttransplant outcomes.
