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Efficacy of Home-Based Versus Hospital-Based Disimpaction with Polyethylene Glycol in Pediatric Functional

Srinivas Srinidhi Vadlapudi1, Ujjal Poddar2, Anshu Srivastava1

  • 1Department of Pediatric Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Raebareli Road, Lucknow, Uttar Pradesh, 226014, India.

Digestive Diseases and Sciences
|April 16, 2025
PubMed

Insights

Home-based disimpaction using polyethylene glycol (PEG) is as effective as hospital-based treatment for childhood functional constipation. This approach offers a lower cost, fewer side effects, and greater parental satisfaction.

Area of Science:

  • Pediatric Gastroenterology
  • Clinical Pharmacology

Background:

  • Functional constipation (FC) is a prevalent condition in children, often necessitating disimpaction.
  • Polyethylene glycol (PEG) is a common agent for disimpaction, administered either continuously in hospitals or over several days at home.

Purpose of the Study:

  • To compare the efficacy, side effects, cost-effectiveness, and parental satisfaction of home-based versus hospital-based PEG disimpaction in children with FC.

Main Methods:

  • A randomized controlled trial enrolled 115 children (ages 1-18) diagnosed with FC and fecal impaction.
  • Children were randomized to receive PEG disimpaction in a hospital setting or at home.
  • Efficacy, side effects, treatment costs, and parental satisfaction (using TSQM) were assessed.

Main Results:

  • Successful disimpaction rates were high in both groups (100% hospital-based vs. 94.7% home-based).
  • Hospital-based disimpaction was associated with significantly higher rates of vomiting and abdominal distension.
  • Home-based disimpaction incurred lower treatment costs and yielded greater parental satisfaction.

Conclusions:

  • Home-based PEG disimpaction is a safe and effective alternative to hospital-based treatment for childhood functional constipation.
  • The home setting is preferred due to reduced side effects, lower costs, and improved parental satisfaction.
Abstract

Keywords:
DisimpactionFecal impactionFunctional constipationPolyethylene glycol

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