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Modified zipper method in steroid-resistant ADEM: a case report

Nihal Akçay1, İlyas Bingöl1, Hilal Merve Dolu2

  • 1Department of Pediatric Intensive Care Unit, University of Health Sciences Kanuni Sultan Suleyman Training and Research Hospital, Istanbul, 34303, Turkey.

Acta Neurologica Belgica
|April 16, 2025
PubMed
Summary

Steroid-resistant acute disseminated encephalomyelitis (ADEM) in a child improved with a modified zipper technique, combining intravenous immunoglobulin (IVIG) and therapeutic plasma exchange (TPE). This novel approach offers a promising alternative for challenging ADEM cases.

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