Increase in blood pressure in pheochromocytoma induced by domperidone and metoclopramide

Administration of two dopamine antagonists, domperidone and metoclopramide, gave a marked rise in blood pressure with an increase in plasma catecholamines in two patients with pheochromocytoma. The result suggests that not only metoclopramide but also domperidone might induce hypertensive crisis in pheochromocytoma.