Related Experiment Video

Updated: May 11, 2025

Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion
08:35

Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion

Published on: May 26, 2022

3.0K

Stroke Outcomes in a Population-Focused Urban Hypertension Program in Brazil and Senegal

Jose Maria E Ferrer1, Johannes Boch2, Ann Aerts2

  • 1American Heart Association Dallas Texas USA.

Journal of the American Heart Association
|April 16, 2025
PubMed

Insights

Implementing the CARDIO4Cities initiative significantly reduced stroke hospitalizations and deaths in urban areas of Senegal and Brazil. This multisectoral approach to blood pressure control shows rapid, positive impacts on cardiovascular health outcomes.

Area of Science:

  • Public Health
  • Cardiovascular Epidemiology
  • Global Health Initiatives

Background:

  • Stroke remains a leading cause of death globally, particularly in low- and middle-income countries.
  • Multifaceted strategies targeting blood pressure control are crucial for mitigating the global stroke burden.
  • Urban environments present unique challenges and opportunities for cardiovascular health interventions.

Purpose of the Study:

  • To evaluate the impact of the multisector urban cardiovascular health initiative (CARDIO4Cities) on stroke outcomes.
  • To assess stroke hospitalization and mortality trends in Dakar, Senegal, and São Paulo, Brazil, following the intervention.
  • To determine the effectiveness of population-level interventions in reducing cardiovascular risk and improving hypertension management.

Main Methods:

  • Utilized an interrupted time series analysis and segmented regression to analyze temporal trends in stroke outcomes.
  • Employed generalized linear models to assess the relative risk of stroke hospitalization.
  • Compared intervention and control districts in São Paulo, analyzing data from preintervention, intervention, and follow-up periods (2016-2021).

Main Results:

  • Both Dakar and São Paulo observed significant declines in age-standardized stroke hospitalization rates (Dakar: -26%; São Paulo: -54%).
  • Stroke mortality rates also decreased in both cities during the intervention period.
  • In São Paulo, intervention districts showed a 24.5% lower risk of stroke hospitalization compared to control areas post-intervention.

Conclusions:

  • The multisectoral CARDIO4Cities initiative demonstrated a correlation with positive trends in stroke outcomes.
  • Population-level interventions for cardiovascular risk reduction and hypertension management can rapidly decrease stroke hospitalizations and mortality.
  • This study highlights the potential of integrated urban health initiatives to address the global burden of stroke.
Abstract

Keywords:
cardiovascular diseasecardiovascular riskhypertensionpopulation healthstrokeurban

More Related Videos

Hydra, a Computer-Based Platform for Aiding Clinicians in Cardiovascular Analysis and Diagnosis07:51

Hydra, a Computer-Based Platform for Aiding Clinicians in Cardiovascular Analysis and Diagnosis

Published on: September 26, 2018

7.5K
Setting Up a Stroke Team Algorithm and Conducting Simulation-based Training in the Emergency Department - A Practical Guide09:52

Setting Up a Stroke Team Algorithm and Conducting Simulation-based Training in the Emergency Department - A Practical Guide

Published on: January 15, 2017

17.1K

Related Concept Videos

Errors occurring during blood pressure monitoring01:25

Errors occurring during blood pressure monitoring

Blood pressure monitoring is a crucial clinical procedure in diagnosing and managing various cardiovascular conditions. Despite its significance, the accuracy of blood pressure measurements can be compromised by multiple factors, potentially leading to either falsely high or low readings. These inaccuracies are critical as they can significantly impact patient care. So, it is vital to understand these challenges deeply and adopt strategic approaches to minimize errors.
Several factors...
565
Pre-Procedural Guidelines for Assessing Blood Pressure01:10

Pre-Procedural Guidelines for Assessing Blood Pressure

Accurate blood pressure assessment is crucial for diagnosing and managing various health conditions. To ensure the reliability of these measurements, healthcare professionals must adhere to standardized pre-procedural guidelines. These guidelines enhance patient safety and improve the overall quality of healthcare. The following steps are essential for obtaining accurate and consistent blood pressure readings, from using the appropriate tools to ensuring effective communication with the...
509
Assessing Blood pressure in the Leg01:11

Assessing Blood pressure in the Leg

Proper measurement of leg blood pressure is a critical skill for healthcare providers, ensuring precise and reliable readings. When performed correctly, this procedure informs patient care and enhances the efficacy of interventions. The following text outlines step-by-step guidelines to measure blood pressure in the leg, providing clarity and ease of understanding for practitioners.
Preparation:
1.6K
Hypertension and Regulation of Blood Pressure01:18

Hypertension and Regulation of Blood Pressure

Hypertension, the most common cardiovascular disease, is diagnosed through repeated measurements of elevated blood pressure. Its risks, including damage to the kidney, heart, and brain, are directly proportional to blood pressure levels. Starting from 115/75 mm Hg, the risk of cardiovascular disease doubles with each increment of 20/10 mm Hg. The diagnosis relies on blood pressure measurements, not on patient symptoms, as hypertension is often asymptomatic until end-organ damage is imminent or...
1.8K
Assessment of blood pressure in brachial artery(two-step method)01:23

Assessment of blood pressure in brachial artery(two-step method)

Measuring blood pressure is a fundamental skill in healthcare that aids in diagnosing and monitoring hypertension and other cardiovascular conditions. An aneroid sphygmomanometer, commonly used in clinical settings, offers a manual and precise method for blood pressure measurement. The technique for using this instrument involves specific steps that must be carefully executed to ensure accuracy. The following detailed description outlines a two-step technique for assessing blood pressure using...
624
Assessment of blood pressure in brachial artery(one-step method)01:15

Assessment of blood pressure in brachial artery(one-step method)

This procedural guide systematically measures blood pressure using an oscillometric digital sphygmomanometer, emphasizing accuracy, patient safety, and comfort.
Prepare for the Procedure:
546