Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Burn Injuries01:22

Burn Injuries

Burn injuries occur when the skin and underlying tissues are damaged due to exposure to heat, electricity, chemicals, radiation, or friction. They can vary in severity, from minor superficial burns to severe deep burns that can be life-threatening.
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Younger age at colorectal cancer diagnosis in hereditary gastrointestinal cancer predisposition syndromes and Lynch syndrome: a nationwide analysis.

Journal of gastrointestinal oncology·2026
Same author

Sodium Alginate-Based Submucosal Lifting Hydrogel for Endoscopic Mucosal Resection and Endoscopic Submucosal Dissection.

Advanced healthcare materials·2026
Same author

Ethnicity, trial era, and timing: reappraising heterogeneity in the clopidogrel vs aspirin meta-analysis for chronic coronary syndromes.

European heart journal·2026
Same author

Risk of Myeloproliferative Neoplasms in Patients With Inflammatory Bowel Disease and Impact on Outcomes: A Multi-Centre Matched Analysis.

Alimentary pharmacology & therapeutics·2026
Same author

Cost-Utility Analysis of High-Intensity Statins; Atorvastatin 40 and 80 mg versus Rosuvastatin 20 mg from Egyptian Public Payer's Perspective: A Markov Model.

International journal of preventive medicine·2026
Same author

ECG-Guided Conduction Pathways as a Lever to Shorten Post-TAVI Hospitalization.

The American journal of cardiology·2026

Related Experiment Video

Updated: May 11, 2026

Rat Burn Model to Study Full-Thickness Cutaneous Thermal Burn and Infection
08:40

Rat Burn Model to Study Full-Thickness Cutaneous Thermal Burn and Infection

Published on: August 23, 2022

4.5K

New burn model for developing consistent second- and third-degree burn injuries in rats.

Ahmed Ibrahim1, Khaled M A Hassanein2, Mahmoud Soliman2

  • 1Veterinary Teaching Hospital, Faculty of Veterinary Medicine, Assiut University, Assiut, 71526, Egypt. elgrah38@vet.aun.edu.eg.

BMC Research Notes
|April 16, 2025
PubMed
Summary

A digital drying oven provides a reliable method for creating consistent burn models in rats. Specific temperatures with a stainless-steel rod create reproducible second and third-degree burn injuries.

Keywords:
BurnDrying ovenModelRatStainless steel

More Related Videos

Author Spotlight: A Multi-Depth Porcine Model for Comprehensive Study of Burn Injuries and Healing Processes
02:49

Author Spotlight: A Multi-Depth Porcine Model for Comprehensive Study of Burn Injuries and Healing Processes

Published on: February 23, 2024

886
Chessboard-like Burn Wound Healing Model of Mice Based on Digital Heating Device
04:04

Chessboard-like Burn Wound Healing Model of Mice Based on Digital Heating Device

Published on: December 27, 2024

340

Related Experiment Videos

Last Updated: May 11, 2026

Rat Burn Model to Study Full-Thickness Cutaneous Thermal Burn and Infection
08:40

Rat Burn Model to Study Full-Thickness Cutaneous Thermal Burn and Infection

Published on: August 23, 2022

4.5K
Author Spotlight: A Multi-Depth Porcine Model for Comprehensive Study of Burn Injuries and Healing Processes
02:49

Author Spotlight: A Multi-Depth Porcine Model for Comprehensive Study of Burn Injuries and Healing Processes

Published on: February 23, 2024

886
Chessboard-like Burn Wound Healing Model of Mice Based on Digital Heating Device
04:04

Chessboard-like Burn Wound Healing Model of Mice Based on Digital Heating Device

Published on: December 27, 2024

340

Area of Science:

  • Biomedical Engineering
  • Wound Healing Research
  • Animal Models in Research

Background:

  • Accurate and reproducible burn models are crucial for studying wound healing and testing therapies.
  • Traditional methods for creating burn injuries in animal models can lack consistency and control.

Purpose of the Study:

  • To introduce a digital drying oven as a precise tool for burn model creation.
  • To determine optimal heating temperatures for inducing consistent second and third-degree burns in rats.

Main Methods:

  • Utilized a digital drying oven to heat a stainless-steel rod (63 g, 8 mm).
  • Applied the heated rod to rat skin for 30 seconds at varying temperatures (100°C, 150°C, 200°C).
  • Assessed burn depth and characteristics microscopically.

Main Results:

  • Heating at 100°C produced second-degree burns (epidermal and upper dermal necrosis).
  • Heating at 150°C and 200°C resulted in third-degree burns (full-thickness dermal necrosis extending to subcutaneous tissue).
  • Burn depths were significantly greater at 150°C and 200°C compared to 100°C (P < 0.001).

Conclusions:

  • The digital drying oven is a reliable, reproducible, and controllable device for burn model generation.
  • A 30-second application of a stainless-steel rod heated to 100°C and 150°C effectively creates second and third-degree burns in rats, respectively.