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Updated: May 5, 2026

Controlled Cortical Impact Model for Traumatic Brain Injury
Published on: August 5, 2014
The Effect of an Integrative Cognitive Training Program by Family Caregivers on Cognitive Function Among Persons With
Uraporn Chuaykarn1,2, Ratsiri Thato1, Elizabeth A Crago3
1Center of Excellence for Enhancing Well-being in Vulnerable and Chronic Illness Populations, Faculty of Nursing, Chulalongkorn University, Bangkok, Thailand.
Family caregivers providing integrative cognitive training significantly improved cognitive function in individuals with traumatic brain injury (TBI). This approach enhances neuroplasticity and community engagement for better rehabilitation outcomes.
Area of Science:
- Neuroscience
- Rehabilitation Medicine
- Cognitive Psychology
Background:
- Traumatic brain injury (TBI) can lead to significant cognitive impairments.
- Family caregiver involvement is crucial for effective TBI rehabilitation.
- Existing rehabilitation programs may not fully leverage caregiver potential.
Purpose of the Study:
- To evaluate the efficacy of an integrative cognitive training program delivered by family caregivers for individuals with mild-to-moderate TBI.
- To assess the impact of this intervention on cognitive function and neuroplasticity.
Main Methods:
- A randomized controlled trial with a repeated measures design was conducted.
- 100 participants with mild-to-moderate TBI and their family caregivers were recruited.
- The experimental group received caregiver-led cognitive training, while the control group received usual care; cognitive function was assessed using the Montreal Cognitive Assessment.
Main Results:
- The experimental group showed significant improvements in cognitive function over the 6-week study period (p < 0.001).
- Participants receiving caregiver-led training demonstrated significantly higher cognitive function scores compared to the control group at weeks 4 and 6 (p < 0.001).
- Large effect sizes (η² = 0.14) and high statistical power (90%) indicated a robust intervention effect.
Conclusions:
- An integrative cognitive training program, when delivered by family caregivers, effectively enhances neuroplasticity and improves cognitive function in TBI patients.
- Involving family caregivers in rehabilitation promotes community integration and cognitive recovery.
- Healthcare professionals should integrate this training into standard care and empower caregivers to continue interventions at home.
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