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A lightweight multi-deep learning framework for accurate diabetic retinopathy detection and multi-level severity
Amad Zafar1, Kwang Su Kim2, Muhammad Umair Ali1
1Department of Artificial Intelligence and Robotics, Sejong University, Seoul, Republic of Korea.
Frontiers in Medicine
|April 17, 2025
Summary
A new lightweight deep learning model accurately detects diabetic retinopathy (DR) and its severity using a two-stage approach. This method offers efficient and precise analysis of fundus images for improved patient care.
Area of Science:
- Ophthalmology
- Medical Imaging
- Artificial Intelligence
Background:
- Diabetic retinopathy (DR) detection requires timely analysis of complex fundus images.
- Developing accurate automated algorithms for DR diagnosis remains a significant challenge.
- Early detection and classification of DR are critical for effective patient management and preventing vision loss.
Purpose of the Study:
- To present a novel, lightweight deep learning network for the detection and severity subclassification of diabetic retinopathy.
- To develop a two-stage framework that first identifies the presence of DR and then classifies its severity.
- To demonstrate the efficacy of transfer learning using a pre-trained model for enhanced DR subclassification.
Main Methods:
- A lightweight deep learning network was designed for DR detection.
- A two-stage classification approach was implemented: presence of DR and then DR severity subclassification (mild, moderate, severe, proliferative).
- Transfer learning was utilized in the second stage, reusing the designed model for severity classification on correlated fundus images.
Main Results:
- The proposed model is lightweight with fewer learnable parameters compared to existing methods.
- The two-stage framework achieved a 99.06% classification rate for DR detection.
- The model attained 90.75% accuracy for DR severity identification on the APTOS 2019 dataset.
Conclusions:
- The developed lightweight deep learning network provides an efficient solution for DR detection.
- The two-stage approach significantly enhances classification performance for both DR presence and severity.
- This framework shows promise for improving automated analysis of fundus images in clinical settings.

