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Immunotherapy-Related Sialadenitis
1Internal Medicine, Moffitt Cancer Center, Tampa, USA.
Cureus
|April 17, 2025
Abstract:
Sialadenitis is an inflammation of one or more of the salivary glands. A 21-year-old genetic female undergoing combination ipilimumab/nivolumab therapy for metastatic melanoma presented to our hospital with anterior neck swelling. CT imaging demonstrated bilateral submandibular gland sialadenitis. The clinical picture was most consistent with immunotherapy-related sialadenitis, and the patient responded promptly to systemic corticosteroids.
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