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Enhancement using CIRCLE software post cornea lenticule extraction for advanced refractive correction.
Gitansha S Sachdev1, Tasneem Neemuchwala, Shreyas Ramamurthy
1Refractive Services, The Eye Foundation, Coimbatore, Tamil Nadu, India.
Indian Journal of Ophthalmology
|April 17, 2025
Summary
Enhancement using CIRCLE software after corneal lenticular extraction (CLEAR) significantly improved visual acuity. This safe procedure offers a viable option for refractive correction enhancement.
Area of Science:
- Ophthalmology
- Refractive Surgery
- Corneal Surgery
Background:
- Corneal lenticular extraction (CLEAR) is used for advanced refractive correction.
- Enhancement procedures are sometimes necessary for under-correction or regression after primary CLEAR.
Purpose of the Study:
- To evaluate the visual outcomes of enhancement procedures following CLEAR using CIRCLE software.
- To assess the safety and efficacy of the CIRCLE software for retreatment.
Main Methods:
- A prospective study involving eyes requiring enhancement after CLEAR.
- CIRCLE software was used to create a flap, followed by excimer laser ablation to a plano target.
- Visual acuity and safety outcomes were analyzed at three months post-enhancement.
Main Results:
- Mean preoperative spherical equivalent was -5.04 D, with enhancement addressing a residual error of -0.86 D.
- Final manifest spherical equivalent was -0.01 D, with significant improvement in uncorrected distance visual acuity (UDVA).
- 78% of eyes achieved 20/20 or better UDVA post-enhancement, with no loss of corrected distance visual acuity (CDVA) or major complications.
Conclusions:
- CIRCLE software provides a safe and effective option for visual enhancement after CLEAR.
- This retreatment modality can successfully correct residual refractive errors and improve visual function.

