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Stimulus-Secretion Coupling Mechanisms of Glucose-Induced Insulin Secretion: Biochemical Discrepancies Among the

Jorge Tamarit-Rodriguez1

  • 1Biochemistry Department, Medical School, Complutense University, 28040 Madrid, Spain.

International Journal of Molecular Sciences
|April 17, 2025
PubMed

Keywords:
ADP privationATP demand by insulin gene translationGABA-shunt modelscanonicalcell hierarchy of ATP consumer processesinsulin secretionpancreatic islet metabolismsulfonylureas and β-cell metabolismβ-cell OxPhos regulationβ-cell glycolysisβ-cell lactate releaseβ-cell mitochondrial ATP supply versus ATP demandβ-cell mitochondrial alterations in T2D isletsβ-cell secretion coupling mechanisms

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