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RISK FACTORS FOR POSTOPERATIVE PANCREATIC FISTULA FOLLOWING PANCREATICODUODENECTOMY: TUNISIAN CENTER EXPERIENCE
Nizar Khedhiri1,2, Haithem Zaafouri1,2, Wael Boujelbene1,2
1Habib Thameur Hospital, General Surgery - Tunis, Tunísia.
Summary
Soft pancreatic texture is the sole independent risk factor for postoperative pancreatic fistula (POPF) after pancreaticoduodenectomy (PD). Further research is needed to confirm POPF risk factors.
Area of Science:
- Digestive Surgery
- Surgical Oncology
- Gastroenterology
Background:
- Pancreaticoduodenectomy (PD) is a significant surgical procedure with low mortality but high morbidity.
- Postoperative pancreatic fistula (POPF) is the predominant complication following PD.
Purpose of the Study:
- To identify and analyze risk factors associated with POPF after PD.
- To improve patient outcomes by understanding POPF predictors.
Main Methods:
- Retrospective analysis of 50 patients undergoing PD between 2010-2021.
- Evaluation of patient demographics, surgical techniques, and postoperative outcomes.
- Statistical analysis including univariate and multivariate assessments of risk factors.
Main Results:
- The overall POPF rate was 32%, with Grade C fistulas in 20% of patients.
- Univariate analysis identified pancreatic duct diameter ≤3 mm, soft pancreas texture, specific suturing techniques, and blood glucose levels as potential risk factors.
- Multivariate analysis revealed soft pancreatic texture as the only independent predictor of POPF.
Conclusions:
- Soft pancreatic texture is confirmed as the primary independent risk factor for POPF.
- Further prospective studies are essential to definitively establish all risk factors for POPF post-PD.
