Related Experiment Video
Updated: Jun 13, 2025

07:04
Confocal Time Lapse Imaging as an Efficient Method for the Cytocompatibility Evaluation of Dental Composites
Published on: November 9, 2014
13.6K
Long-Term Whitening Stability in Combined In-Office and At-Home Whitening Protocols: A Randomized Controlled Clinical
Toshiki Takamizawa1, Rei Muto1, Shunichi Suda1
1Department of Operative Dentistry, Nihon University School of Dentistry, Tokyo, Japan.
Summary
Combining in-office and at-home whitening with prefilled trays offers superior, long-lasting tooth whitening results compared to in-office treatments alone. This approach enhances overall whitening efficacy over a two-year period.
Area of Science:
- Dental Aesthetics
- Materials Science in Dentistry
Background:
- Tooth discoloration is a common aesthetic concern.
- Professional whitening treatments aim to improve tooth shade and appearance.
Purpose of the Study:
- To evaluate the long-term color stability of combined tooth whitening protocols.
- To compare the efficacy of in-office whitening combined with at-home prefilled trays versus in-office whitening alone for up to two years.
Main Methods:
- A randomized clinical study involving 66 participants divided into three groups.
- Group I: 10 at-home sessions between 3 in-office sessions. Group II: 5 at-home sessions between 3 in-office sessions. Group III: 3 in-office sessions only.
- Tooth color measured using a spectrophotometer at baseline and multiple follow-ups up to 2 years, analyzed with CIELAB ΔE*ab, CIE DE2000 ΔE00, and ΔWID.
Main Results:
- All groups showed a gradual decrease in ΔE*ab and ΔE00 over time.
- Groups II and III demonstrated significantly reduced ΔWID in early follow-up periods compared to Group I.
- Combined whitening protocols exhibited varying color stabilities depending on the technique.
Conclusions:
- Combined in-office and at-home whitening using prefilled trays provides more durable whitening effects.
- This combination therapy surpasses the longevity of in-office whitening performed solely.
- Prefilled tray systems integrated with professional treatments enhance sustained aesthetic outcomes.

