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Updated Human Chromosome Map of Lymphedema-lymphangiogenesis Genes: Template for Current and Future Discovery

P Brouillard1, M H Witte2,3,4, R P Erickson2,3,4

  • 1Human Molecular Genetics, de Duve Institute, University of Louvain, Brussels, Belgium.

Lymphology
|April 17, 2025
PubMed

Keywords:
chromosomesgenesmutationsprimary lymphedema

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In 1882, Flemming observed lampbrush chromosomes (LBC) in salamander eggs. Later in 1892, Rückert observed LBCs in shark egg cells and coined the term "lampbrush chromosomes" because they looked like brushes used to clean kerosene lamps.
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