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Punctured window based multiscale line detector for efficient segmentation of retinal blood vessels
Varun Makkar1, Arya Tewary1, B V Rathish Kumar2
1Department of Mathematical Sciences, Indian Institute of Technology (BHU) Varanasi, Varanasi 221005, Uttar Pradesh, India.
Computers in Biology and Medicine
|April 17, 2025
Summary
This study introduces an improved automated algorithm for retinal vessel segmentation, enhancing detection of small vessels in low-contrast areas. The novel method offers accurate segmentation for diagnosing eye diseases.
Area of Science:
- Ophthalmology
- Medical Imaging
- Computer Vision
Background:
- Retinal vasculature changes are key indicators for diagnosing diseases like diabetes and hypertension.
- Accurate segmentation of retinal vessels is crucial for efficient diagnosis and cost-effective treatment.
Purpose of the Study:
- To develop an automated algorithm for retinal vasculature segmentation.
- To improve upon classic line detector methods by addressing background intensity estimation flaws.
Main Methods:
- A novel 'punctured window' approach is introduced to enhance line detection in low-contrast regions.
- Image denoising using a fractional filter, followed by multi-scale line detection with punctured windows.
- Final segmentation achieved through hysteresis thresholding after combining multi-scale responses and underlying image intensity.
Main Results:
- The algorithm demonstrates enhanced ability to identify minor vessels in low-contrast areas.
- Tested on four public datasets (RC-SLO, STARE, CHASE_DB1, DRIVE) using class imbalance-unaffected metrics.
- The proposed technique shows comparable performance to state-of-the-art methods, outperforming many.
Conclusions:
- The enhanced line detector with punctured windows significantly improves retinal vessel segmentation accuracy.
- The algorithm provides a robust and consistent performance across multiple datasets and metrics.
- This automated method facilitates efficient diagnosis of retinal vascular diseases.

