[Urinary catecholamines in normal-weight and overweight diabetics]

The 24-h urine excretion of free, conjugated and total fraction of Dopa, dopamine, noradrenaline and adrenaline was studied in diabetics with normal weight and overweight. A tendency to lower excretion of adrenaline, noradrenaline and dopamine was established in diabetics with overweight as well as a tendency to reverse correlation between overweight and urine excretion of catecholamines. On the base of the so called synthesis and degradation coefficients, the possibility the changes established in the diabetics with overweight to be due to reduced synthesis of dopamine and noradrenaline is discussed. A presumption is presented about the possible causative relation between the reduction of catecholamine excretion and overweight in diabetics.