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Critical Appraisal of: Systematic Review and Meta-Analysis Assessing GnRH Antagonists, Considering Add-Back Therapy,

Sylvie Bowden1, Jena Hall2

  • 1Department of Obstetrics and Gynecology, Cumming School of Medicine, University of Calgary, Calgary, AB.

Journal of Obstetrics and Gynaecology Canada : JOGC = Journal D'Obstetrique Et Gynecologie Du Canada : JOGC
|April 17, 2025
PubMed
Abstract

No abstract available in PubMed .

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Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
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