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Effects of community-acquired pneumonia on biventricular cardiac functions in children
Rehab Elmeazawy1, Esraa Abd Al-Fattah Sorour2, Al Shimaa Badreldeen3
1Department of Pediatrics, Faculty of Medicine, Tanta University, Tanta, Egypt. rehab.elmeazawy@med.tanta.edu.eg.
Insights
Community-acquired pneumonia (CAP) in children can impair biventricular cardiac function. Advanced echocardiography techniques like tissue Doppler imaging (TDI) and 2D speckle tracking echocardiography (2D-STE) effectively detect this early cardiac dysfunction.
Area of Science:
- Pediatric Cardiology
- Echocardiography
- Cardiovascular Imaging
Background:
- Community-acquired pneumonia (CAP) can lead to cardiac complications in children.
- Early detection of biventricular cardiac dysfunction is crucial for managing pediatric CAP.
- Conventional echocardiography may not always detect subtle cardiac changes in pediatric CAP.
Purpose of the Study:
- To evaluate the impact of CAP on cardiac function in children.
- To compare the effectiveness of TDI and 2D-STE with conventional echocardiography for early detection of biventricular dysfunction in pediatric CAP.
Main Methods:
- The study included 50 children hospitalized with CAP and 50 healthy controls.
- Cardiac function was assessed using conventional echocardiography, TDI, and 2D-STE.
- Key echocardiographic parameters of biventricular function were analyzed.
Main Results:
- Children with CAP exhibited significantly impaired left ventricular systolic function and right ventricular diastolic function compared to controls.
- Both ventricles showed significantly higher myocardial performance index (MPI) in the CAP group.
- Two-dimensional longitudinal strain (2D LS) was significantly reduced in children with CAP.
Conclusions:
- TDI and 2D-STE are valuable tools for detecting early biventricular dysfunction in pediatric CAP.
- These advanced echocardiographic methods offer improved sensitivity for identifying cardiac involvement in pediatric CAP.
- The findings support the use of TDI and 2D-STE in the routine evaluation of children with CAP.
Background:
This study aimed to evaluate the effects of community-acquired pneumonia (CAP) on cardiac function in children and compare the effectiveness of tissue Doppler imaging (TDI) and two-dimensional speckle tracking echocardiography (2D-STE) with conventional echocardiography in the early detection of biventricular cardiac dysfunction in children with CAP.
Methods:
The study included 50 hospitalized children diagnosed with CAP and 50 matched healthy controls. All patients underwent cardiac evaluation including conventional echocardiography, TDI, and 2D-STE.
Results:
Fifty children with CAP with a mean age of 5.02 ± 2.46 years participated in the study. Thirty-two were male (64.0%). LV systolic function (S) and RV diastolic function (E'/A') were significantly lower in the diseased group compared to the control group (p < 0.001). The myocardial performance index (MPI) of both ventricles was significantly higher in the diseased group compared to the control group (p < 0.001). In patients with CAP, the mean value of two-dimensional longitudinal strain (2D LS) was significantly lower than that of the control group (p < 0.001). No statistically significant differences in echocardiographic parameters were observed when comparing complicated and non-complicated CAP subgroups.
Conclusion:
TDI and 2D-STE demonstrated the ability to detect early biventricular dysfunction in pediatric patients diagnosed with CAP.
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