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Boosting macroscopic diffusion with local resetting
Henry Alston1, Thibault Bertrand1
1Imperial College London, Department of Mathematics, South Kensington, London SW7 2AZ, United Kingdom.
Physical Review. E
|April 18, 2025
Summary
Stochastic resetting enhances self-diffusion in biological systems. Optimized regular resetting sites maximize this diffusion enhancement, offering insights into transport properties.
Area of Science:
- Physics
- Biophysics
- Statistical Mechanics
Background:
- Stochastic interactions are known to enhance self-diffusivity in biological systems, crucial for processes like navigation and tissue mechanics.
- The underlying physical mechanisms driving this nonequilibrium enhancement remain poorly understood.
- Understanding these mechanisms is key to controlling transport properties in cellular and bacterial systems.
Purpose of the Study:
- To introduce and analyze a model of stochastic resetting for understanding enhanced self-diffusivity.
- To derive analytic results for the self-diffusion coefficient under this resetting mechanism.
- To investigate how the arrangement of resetting sites affects diffusion enhancement.
Main Methods:
- Development of a theoretical model incorporating a local stochastic resetting mechanism.
- Analytical derivation of the self-diffusion coefficient.
- Mathematical analysis of the impact of resetting site regularity on diffusivity.
Main Results:
- The proposed stochastic resetting mechanism demonstrably enhances self-diffusivity.
- Analytic results explicitly show the enhancement of the diffusion coefficient.
- The enhancement of diffusivity is found to be optimized by regular arrays of resetting sites.
Conclusions:
- Stochastic resetting is a viable mechanism for enhancing self-diffusivity in diffusive systems.
- Regular arrangements of resetting sites offer an optimal strategy for maximizing diffusion.
- The findings provide conditions for optimizing macroscopic transport in systems with local binding interactions.

