Related Experiment Video
Updated: May 11, 2025

Measuring Influenza Neutralizing Antibody Responses to AH3N2 Viruses in Human Sera by Microneutralization Assays Using MDCK-SIAT1 Cells
Published on: November 22, 2017
Estimating the Waning Effectiveness of COVID-19 Vaccines From Population-Level Surveillance Data in Hong Kong
Haoling Chen1, Xiaotong Huang1, Can Wang1
1WHO Collaborating Centre for Infectious Disease Epidemiology and Control, School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, China.
Abstract:
Assessing the time-varying effectiveness of coronavirus disease 2019 (COVID-19) vaccines is critical to guiding vaccine strategies and public health policies. We developed a Bayesian framework to estimate the waning vaccine effectiveness of various doses of CoronaVac and Comirnaty based on population-level surveillance data. We applied this framework to data on a large Omicron BA.2 epidemic in Hong Kong from January to May 2022. Our results indicated that despite high vaccination rates during this period, high vaccine uptake mitigated but did not prevent rapid spread of infection.
More Related Videos
Related Concept Videos
Vaccinations
Viral Mutations
Steps in Outbreak Investigation

