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Published on: May 8, 2018
Multimodal treatment for colorectal liver metastases: A toolbox for clinicians
Sheraz Yaqub1,2, Anne Longva3,4, Jon-Helge Angelsen5,6
1Department of Hepatopancreatobiliary Surgery Oslo University Hospital P.O. Box 4950 Nydalen Oslo N-0372 Norway.
Abstract:
Colorectal cancer is the second most common cause of cancer-related death worldwide, and liver metastases are the leading cause of mortality in these patients. Surgical innovations combined with modern systemic chemotherapy have improved 5-year overall survival rates. This review aims to equip non-hepatobiliary surgeons with a comprehensive toolbox for the diagnosis and management of colorectal liver metastases. It covers the current landscape of diagnostic workup, including imaging modalities and biomarkers, and reviews the surgical and nonsurgical treatment options. This guide attempts to enhance multidisciplinary care for patients with colorectal liver metastases by integrating evidence-based practices with innovative strategies, which can improve outcomes and survival.
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