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Related Concept Videos

Overview of Systemic and Pulmonary Circulation01:15

Overview of Systemic and Pulmonary Circulation

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The systemic and pulmonary circuits are crucial components of the circulatory system, working together to transport blood between the heart, lungs, and the rest of the body. The process begins with pulmonary circulation, where deoxygenated blood is pumped from the right ventricle to the lungs via the pulmonary trunk and arteries. Upon reaching the lungs, the blood becomes oxygenated and returns to the heart, specifically to the left atrium, via the pulmonary veins.
The oxygenated blood is sent...
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Overview of Pulmonary Circulation01:19

Overview of Pulmonary Circulation

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The pulmonary circulation is a vital system in our body that acts as a bridge between the respiratory and cardiovascular systems. It serves as a transport network for deoxygenated blood from the heart to the lungs and then returns oxygen-rich blood back to the heart.
The process begins with the right ventricle of the heart pumping deoxygenated blood into the pulmonary trunk. This large vessel extends about 5 centimeters before splitting into the left and right pulmonary arteries. These arteries...
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Anatomy of the Circulatory System02:03

Anatomy of the Circulatory System

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The human circulatory system consists of blood, blood vessels that carry blood away from the heart, around the body, and back to the heart, and the heart itself, which acts as a central pump. The systemic circuit supplies blood to the whole body, the coronary circuit supplies blood to the heart, and the pulmonary circuit supplies blood flow between the heart and lungs.
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Overview of Systemic Arteries01:11

Overview of Systemic Arteries

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The human body is a complex, well-organized machine, and at the heart of its operations lies the circulatory system. This network of blood vessels, which includes systemic arteries, plays a vital role in maintaining life by transporting nutrients, oxygen, and waste products to and from cells throughout the body.
Systemic circulation is the part of the cardiovascular system that carries oxygenated blood away from the heart to the body's tissues and returns deoxygenated blood back to the...
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Overview of the Cardiovascular System01:14

Overview of the Cardiovascular System

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The cardiovascular system is a vital transportation system in the body. It comprises the heart and blood vessels and facilitates the exchange of gases, nutrients, and waste products.
Heart
The heart is the central pump of the cardiovascular system that circulates blood throughout the body. It comprises two atria receiving the blood and two ventricles pumping blood out of the heart. Their rhythmic contractions, called heartbeats, ensure that blood flow remains continuous.
Blood Vessels
Blood...
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Overview of the Vascular System01:20

Overview of the Vascular System

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The vascular system comprises an extensive network of arteries, capillaries, and veins. The vascular system can be broadly divided into the blood and lymphatic systems. Typically, blood vessels can be categorized into three histological regions: tunica intima, tunica media, and tunica adventitia. The tunica intima consists of a single layer of endothelial cells attached to the basal lamina. Underlying the basal lamina is a connective tissue layer and an elastic lamina that gives stability and...
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Updated: May 11, 2025

Transcutaneous Microcirculatory Imaging in Preterm Neonates
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Systemic and Pulmonary Microcirculation, Double Microcirculation: From Basic Concepts to Treatment Key Points.

Guangjian Wang1, Qingyu Deng2, Jie Wang1

  • 1Department of Critical Care Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Journal of Intensive Care Medicine
|April 18, 2025
PubMed
Summary
This summary is machine-generated.

This review introduces the concept of "double microcirculation," differentiating systemic and pulmonary microcirculations. Understanding these distinct microcirculatory systems is crucial for improving critical care and patient outcomes.

Keywords:
critical illnesscritically ill patientdouble microcirculationdouble microcirculation protectionpulmonary microcirculationsystemic microcirculationtreatment key point

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Area of Science:

  • Physiology
  • Critical Care Medicine
  • Cardiovascular Research

Background:

  • Macrocirculation is divided into systemic and pulmonary circulation.
  • Microcirculation is rarely subdivided in clinical practice, despite its role in critical illness.
  • Current treatments may overlook microcirculatory heterogeneity in critically ill patients.

Purpose of the Study:

  • To differentiate systemic and pulmonary microcirculation.
  • To introduce the concept of "double microcirculation."
  • To propose treatment strategies based on double microcirculation protection for improved critical care.

Main Methods:

  • Literature review and conceptual synthesis.
  • Comparative analysis of systemic and pulmonary microcirculation.
  • Discussion of structural, functional, and regulatory differences.

Main Results:

  • Systemic and pulmonary microcirculations exhibit distinct characteristics.
  • The concept of "double microcirculation" highlights patient heterogeneity.
  • Targeting double microcirculation offers refined treatment approaches.

Conclusions:

  • Subdividing microcirculation into systemic and pulmonary components is essential.
  • The "double microcirculation" concept refines understanding of critical illness.
  • Protecting double microcirculation can enhance critical care and patient prognosis.