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Updated: May 11, 2025

Induction and Validation of Cellular Senescence in Primary Human Cells
Published on: June 20, 2018
HuTAge: a comprehensive human tissue- and cell-specific ageing signature atlas
Koichi Himori1, Zhang Bingyuan1, Kazuki Hatta1
1Institute for Glyco-core Research (iGCORE), Tokai National Higher Education and Research System, Nagoya 464-0814, Japan.
Summary:
Ageing is a complex process that involves interorgan and intercellular interactions. To obtain a clear understanding of ageing, cross-tissue single-cell data resources are required. However, a complete resource for humans is not available. To bridge this gap, we developed HuTAge, a comprehensive resource that integrates cross-tissue age-related information from The Genotype-Tissue Expression project with cross-tissue single-cell information from Tabula Sapiens to provide human tissue- and cell-specific ageing molecular information.
Availability And Implementation:
HuTAge is implemented within an R Shiny application and can be freely accessed at https://igcore.cloud/GerOmics/HuTAge/home. The source code is available at https://github.com/matsui-lab/HuTAge.
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