Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Ferritin concentration in cerebrospinal fluid.

C Fehling, I Qvist

    Acta Neurologica Scandinavica
    |June 1, 1985
    PubMed
    Summary

    Cerebrospinal fluid (CSF) ferritin levels were measured in patients with psychosomatic, neurological, and cerebrovascular diseases. High CSF ferritin was observed in patients with intracerebral hematomas, suggesting potential diagnostic utility in specific neurological conditions.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Detection of chromosomal abnormalities, congenital abnormalities and transfusion syndrome in twins.

    Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2007
    Same author

    Naturally conceived twins with monochorionic placentation have the highest risk of fetal loss.

    Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2006
    Same author

    How to identify twins at low risk of spontaneous preterm delivery.

    Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2005
    Same author

    A double blind, randomised, parallel group study to investigate the dose equivalence of Dysport and Botox in the treatment of cervical dystonia.

    Journal of neurology, neurosurgery, and psychiatry·1998
    Same author

    [L-dopa and bromocriptine in Parkinson disease. Early combination therapy has better effect].

    Lakartidningen·1993
    Same author

    [Neurological institutes agree: they suggest new guidelines for handling of suspected vitamin B 12 deficiency].

    Lakartidningen·1992

    Area of Science:

    • Neurology
    • Biochemistry
    • Clinical Diagnostics

    Background:

    • Ferritin, an iron-storage protein, is present in serum and cerebrospinal fluid (CSF).
    • Elevated ferritin levels in CSF may indicate neurological disease or blood-brain barrier dysfunction.
    • Investigating CSF ferritin concentrations can offer insights into various neurological conditions.

    Purpose of the Study:

    • To investigate serum and CSF ferritin concentrations in patients with psychosomatic, miscellaneous neurological, and cerebrovascular diseases.
    • To explore the correlation between serum and CSF ferritin levels.
    • To assess the diagnostic value of CSF ferritin analysis in neurological disorders.

    Main Methods:

    • Serum and CSF samples were collected from patients across different disease groups.
    • Ferritin concentrations were measured using biochemical assays.
    • Statistical analysis was performed to determine mean values, correlations, and significance.

    Main Results:

    • Mean CSF ferritin concentration in the psychosomatic group was 6.2 µg/L.
    • Patients with recent cerebral infarction showed similar CSF ferritin levels.
    • Two patients with intracerebral hematomas exhibited markedly elevated CSF ferritin concentrations.
    • A positive correlation between serum and CSF ferritin was found in patients with a compromised blood-CSF barrier.
    • Correlation between CSF total protein and ferritin was observed only in patients with a damaged blood-CSF barrier.

    Conclusions:

    • CSF ferritin levels may be elevated in specific neurological conditions like intracerebral hematomas.
    • The correlation between serum and CSF ferritin is dependent on the integrity of the blood-CSF barrier.
    • Currently, the clinical utility of analyzing CSF ferritin is limited, requiring further research for broader applications.

    Related Experiment Videos