Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Ultrasound II: Endoscopic Ultrasound and FibroScan01:25

Ultrasound II: Endoscopic Ultrasound and FibroScan

51
Endoscopic Ultrasound (EUS) and FibroScan are valuable diagnostic tools in gastroenterology and hepatology, each with specific applications and techniques.
Endoscopic Ultrasound (EUS):
51

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Increased thyroid stiffness without volume change in systemic sclerosis: a case-control study using two-dimensional shear wave elastography.

Rheumatology international·2026
Same author

Development of a clinical scoring system to predict response to low-intensity shock wave therapy in clinically diagnosed vasculogenic erectile dysfunction: a prospective, non-randomized, single-arm, interventional study.

Sexual medicine·2026
Same author

Prediction of Histopathological Grade of Hepatocellular Carcinoma by Gadoxetic Acid-Enhanced Magnetic Resonance Imaging Radiomics Features.

The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology·2026
Same author

Pediatric lung abscesses: a 13-year journey from diagnosis to treatment.

BMC infectious diseases·2026
Same author

Focal hepatic steatosis as a rare complication of microwave ablation-induced portal vein thrombosis: A radiologic case report.

Hepatology forum·2026
Same author

Evaluation of the coalescent lung ultrasound score in rheumatoid arthritis-associated interstitial lung disease.

Clinical rheumatology·2025

Related Experiment Video

Updated: May 11, 2025

Non-Invasive PET/MR Imaging in an Orthotopic Mouse Model of Hepatocellular Carcinoma
07:47

Non-Invasive PET/MR Imaging in an Orthotopic Mouse Model of Hepatocellular Carcinoma

Published on: August 31, 2022

2.1K

Validation of functional liver imaging scores derived on gadoxetic acid-enhanced MRI in hepatocellular carcinoma

Duygu Ozgul1, Ferhat Can Piskin1, Sinan Sozutok1

  • 1Department of Radiology, Cukurova University School of Medicine, Balcali Hospital, Adana, Turkiye.

Hepatology Forum
|April 18, 2025
PubMed
Summary

Functional Liver Imaging Scores (FLIS) correlate with liver function in hepatocellular carcinoma (HCC) patients. This non-invasive imaging marker aids in assessing liver function and differentiating disease severity.

Keywords:
Gadoxetic acidhepatocellular carcinomaliver function

More Related Videos

Y-90 Radioembolization and PD-1 Inhibitor as Neoadjuvant Treatment in Hepatocellular Carcinoma
09:11

Y-90 Radioembolization and PD-1 Inhibitor as Neoadjuvant Treatment in Hepatocellular Carcinoma

Published on: May 24, 2024

348
Novel In Vivo Micro-Computed Tomography Imaging Techniques for Assessing the Progression of Non-Alcoholic Fatty Liver Disease
08:41

Novel In Vivo Micro-Computed Tomography Imaging Techniques for Assessing the Progression of Non-Alcoholic Fatty Liver Disease

Published on: March 24, 2023

1.0K

Related Experiment Videos

Last Updated: May 11, 2025

Non-Invasive PET/MR Imaging in an Orthotopic Mouse Model of Hepatocellular Carcinoma
07:47

Non-Invasive PET/MR Imaging in an Orthotopic Mouse Model of Hepatocellular Carcinoma

Published on: August 31, 2022

2.1K
Y-90 Radioembolization and PD-1 Inhibitor as Neoadjuvant Treatment in Hepatocellular Carcinoma
09:11

Y-90 Radioembolization and PD-1 Inhibitor as Neoadjuvant Treatment in Hepatocellular Carcinoma

Published on: May 24, 2024

348
Novel In Vivo Micro-Computed Tomography Imaging Techniques for Assessing the Progression of Non-Alcoholic Fatty Liver Disease
08:41

Novel In Vivo Micro-Computed Tomography Imaging Techniques for Assessing the Progression of Non-Alcoholic Fatty Liver Disease

Published on: March 24, 2023

1.0K

Area of Science:

  • Hepatobiliary imaging
  • Liver function assessment
  • Hepatocellular carcinoma (HCC) research

Background:

  • Hepatocellular carcinoma (HCC) poses a significant global health challenge.
  • Accurate assessment of liver function is crucial for HCC patient management.
  • Existing scoring systems may require non-invasive imaging correlates.

Purpose of the Study:

  • To investigate the correlation between Functional Liver Imaging Scores (FLIS) and established liver function scoring systems in HCC patients.
  • To evaluate FLIS as a potential non-invasive biomarker for liver function in HCC.
  • To determine the utility of FLIS in differentiating liver function severity.

Main Methods:

  • Retrospective analysis of 178 HCC patients undergoing gadoxetic acid-enhanced MRI.
  • Evaluation of three hepatobiliary phase parameters for FLIS: parenchymal enhancement, biliary excretion, and portal vein signal intensity.
  • Correlation analysis with Child-Turcotte-Pugh (CTP) classification, Albumin-Bilirubin (ALBI) grade, and Fibrosis-4 (FIB-4) score.

Main Results:

  • A moderate negative correlation was observed between FLIS and both CTP classification (r=-0.596) and ALBI grade (r=-0.513).
  • FLIS demonstrated potential in differentiating between varying severities of liver function.
  • A cut-off FLIS value of ≤3 was identified as optimal for distinguishing between CTP A/B and CTP C patients.

Conclusions:

  • Functional Liver Imaging Scores (FLIS) represent a simple, non-invasive imaging marker for assessing liver function in HCC patients.
  • FLIS shows promise as an adjunct tool for evaluating liver function severity and potentially guiding treatment decisions in HCC.
  • Further validation of FLIS in larger, diverse HCC cohorts is warranted.