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Published on: July 14, 2023
Stimulation-Induced Dyskinesia in STN DBS Patients
Carolina Candeias da Silva1,2, Wilson K W Fung1,3, Duha M Al-Shorafat1,4
1Edmond J. Safra Program in Parkinson's Disease and Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology, University of Toronto, Toronto, Ontario, Canada.
Background:
Stimulation-induced dyskinesia (SID) is a poorly studied and usually transient manifestation of subthalamic deep brain stimulation (STN DBS) for Parkinson's disease (PD), which can be troubling for patients.
Objectives:
The aim of our study was to describe the features and management of SID in PD patients undergoing STN DBS.
Methods:
We conducted a retrospective study among 86 STN DBS patients. Clinical features and volume of tissue activated (VTA) were correlated to SID occurrence.
Results:
SID was identified in 28 (32.6%) patients and persisted for 6 months in six patients (7.0%). VTA overlap with the right motor STN was associated (P < 0.02) with SID. Weaning dopaminergic drugs and reducing the DBS amplitude were the most used strategies to control SID.
Conclusions:
SID is a relatively common complication of STN DBS and can be persistent. It often requires specific postoperative management strategies.
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