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Applying Mendelian randomization to study the relationship between circulating proteins and myocardial infarction

Olga E Titova1, Shuai Yuan2, Susanna C Larsson1,2

  • 1Medical Epidemiology, Department of Surgical Sciences, Uppsala University, Dag Hammarskjölds väg 14 B, 75185 Uppsala, Sweden.

European Heart Journal
|April 18, 2025
PubMed
Summary

No abstract available in PubMed .

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Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
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