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Development and Assessment of a Patient-Reported Outcome Instrument for Gender-Affirming Care.

Manraj N Kaur1, Charlene Rae2, Shane D Morrison3

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This summary is machine-generated.

The GENDER-Q, a new patient-reported outcome measure, was validated in a large international study of transgender and gender diverse adults, demonstrating reliability and validity for gender-affirming care outcomes.

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Area of Science:

  • Health Services Research
  • Psychometrics
  • Transgender Health

Background:

  • Validated patient-reported outcome measures (PROMs) are crucial for assessing gender-affirming care.
  • Existing measures may not adequately capture the experiences of transgender and gender diverse (TGD) individuals.

Purpose of the Study:

  • To field test the GENDER-Q, a novel PROM for gender-affirming care.
  • To evaluate the psychometric properties of the GENDER-Q in a large, international sample of TGD adults.

Main Methods:

  • An international cross-sectional study involving 5497 TGD adults seeking or receiving gender-affirming care.
  • Data collected via online REDCap surveys in multiple languages.
  • Rasch measurement theory (RMT) analysis, test-retest reliability, and construct validity were used to evaluate the GENDER-Q.

Main Results:

  • The GENDER-Q field test included 5497 TGD adults, with diverse gender identities and types of gender-affirming care sought.
  • RMT analysis resulted in 54 unidimensional scales and 2 checklists covering various aspects of care.
  • The GENDER-Q demonstrated good test-retest reliability (ICC >0.70) and supported construct validity, with scores correlating with self-reported outcomes.

Conclusions:

  • The GENDER-Q is a reliable and valid instrument for assessing patient-reported outcomes in gender-affirming care.
  • This validated PROM enables the collection and comparison of evidence-based outcome data from the patient's perspective.
  • The GENDER-Q's international validation supports its use in diverse TGD populations.